Certain antihistamines, a family of drugs that is most typically administered to treat allergies, can be risky for elderly people who are already vulnerable. Diphenhydramine (Benadryl) and chlorpheniramine (Zyrtec) are two first-generation antihistamines that are widely used (Chlor-Trimeton).
Your veterinarian may also offer Temaril-P, an oral prescription allergy drug that contains the antihistamine trimeprazine as well as the steroid prednisolone to help alleviate your pet’s allergies. This drug can be used to treat seasonal allergies as well as flea allergies.
Specifically, first-generation antihistamines have a propensity to create extreme weariness and dryness, which contributes to this phenomenon. Certain antihistamine drugs are particularly linked with dangerous side effects in the elderly, and therefore should be avoided when treating allergy symptoms in the vast majority of cases, especially in the elderly.
When dealing with the general symptoms of rhinitis, it is generally recommended that those in charge of geriatric care provide second generation antihistamines rather than first generation antihistamines. Specifically, first-generation antihistamines have a propensity to create extreme weariness and dryness, which contributes to this phenomenon.
So, what medications are safe for older folks to use for allergy relief? Newer antihistamines like as Claritin® (loratadine) and Allegra® (fexofenadine) are generally considered to be safer and more tolerated, according to Wozniak.
Loratadine, cetrizine, and fexofenadine are all medications with a high level of safety. Clinical trials and medication interaction investigations have all shown that they are safe in terms of cardiovascular safety. This trio of antihistamines has also been demonstrated to be safe in a number of different patient demographics, including children and the elderly.
It is usual practice in the elderly to provide H1-antihistamine therapy for the treatment of rhinitis, conjunctivitis, pruritus, eczema, or urticaria, as well as for the prevention of anaphylactoid responses.
Medications for Allergic Reactions While first generation antihistamines are quite efficient at treating symptoms, they are frequently linked with side effects in older persons such as anxiety, disorientation, drowsiness, impaired vision, diminished mental alertness, urine retention, and constipation, among other things.
This medicine has not been studied in children under the age of 12 for the treatment of year-round allergies, thus there is no information on its safety and efficacy. Cetirizine may have a greater effect on seniors since they are more susceptible to the drug’s effects. As a result, your doctor or pharmacist may recommend that you begin with a reduced starting dose.
If you have narrow-angle glaucoma, severe high blood pressure (hypertension), severe coronary artery disease, or if you are unable to pee, you should not use Zyrtec-D. If you are allergic to hydroxyzine, you should not use Zyrtec-D. (Atarax, Vistaril). If you have used an MAO inhibitor within the last 14 days, you should not take this medication.
The genuine recommendation is that if you are over 65 or have liver or renal problems, you should consult with your doctor to see whether or not it is safe for you to take it. Because Zyrtec is now available as an over-the-counter antihistamine and may be used without a doctor’s supervision, the FDA is just suggesting care in the elderly.
Acrivastine pills, which can be purchased from pharmacies and supermarkets, can be taken by individuals under the age of 65, as well as children aged 12 years and older, according to the manufacturer. Acrivastine is not suggested for adults over the age of 65 due to the fact that very little study has been done on the medication in this age range.
According to one research investigation, Zyrtec has a faster start of action when compared to Claritin and may be more effective than Claritin in decreasing allergy symptoms when compared to Claritin. Of contrast to loratadine, cetirizine, the active component in Zyrtec, has been demonstrated to cause more sleepiness than the latter drug.
A growing body of evidence indicates that age-related alterations occur in the cholinergic system, raising the possibility that significant anticholinergic effects in older persons might lead to a loss in cognitive function, or perhaps provoke delirium. It is possible that diphenhydramine will have severe cognitive and performance-related side effects, especially in young children.
There have been no geriatrics-specific concerns identified in appropriate trials conducted to yet, which would impede the effectiveness of fexofenadine in the aged population. Patients over the age of 65, on the other hand, are more prone to develop age-related renal difficulties, which may necessitate a dose change for those taking fexofenadine.
Patients over the age of 65 are more prone than younger individuals to have age-related liver, renal, or cardiac issues, which may necessitate extra caution and a dose modification for patients using fluticasone nasal spray, according to the American Academy of Dermatology.
For older individuals, Beizer claims that newer forms of antihistamines such as Claritin®, Allegra®, and Zyrtec® have less adverse effects.