The selective serotonin reuptake inhibitors (SSRIs) and the newer antidepressants buproprion, mirtazapine , moclobemide, and venlafaxine (a selective norepinephrine reuptake inhibitor or SNRI) are all relatively safe in the elderly .
Conclusions: Limited evidence suggests that for certain elderly patients, mirtazapine may be preferable to sertraline for treatment of depression. It may also be more cost-effective in patients who have dementia.
However, elderly patients are more likely to have confusion or unusual drowsiness and age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving mirtazapine .
Serious side effects thoughts about harming yourself or ending your life. constant headaches , long-lasting confusion or weakness, or frequent muscle cramps – these can be signs of low sodium levels in your blood (which can cause seizures in severe cases)
To date, there are no known problems associated with long term use of mirtazapine. It is a safe and effective medication when used as directed.
Buspirone is an anti-anxiety drug that has been shown to be effective for older adults. Benzodiazepines , another anti-anxiety drug, are effective but should be prescribed carefully to older adults because of risk of memory impairment, unsteadiness, and falls.
Precautions – while taking mirtazapine It can also cause agitation, aggression and forgetfulness. If you do drink alcohol, drink only small amounts and see how you feel. Do not stop taking your medication. If you have a fever, sore throat or sore mouth while taking mirtazapine , let your doctor know immediately.
Mirtazapine is a newer antidepressant that exhibits both noradrenergic and serotonergic activity. It is at least as effective as the older antidepressants for treating mild to severe depression. Sedation is the most common side effect.
When it comes to antidepressants for seniors, most experts recommend SSRIs or selective norepinephrine reuptake inhibitors (SNRIs), which help increase the brain chemicals serotonin and norepinephrine. These drugs tend to have fewer serious side effects and drug interactions than older antidepressants on the market.
Antidepressants such as sertraline, citalopram, mirtazapine and trazodone are widely prescribed for people with dementia who develop depression. Some recent trials have shown that common antidepressants do not work well in this group, but they may still be tried.
Remeron Tablet Side Effects by Likelihood and Severity Constipation . Dizziness . Drowsiness . Dry Mouth . Generalized Weakness. High Cholesterol. Increased Hunger. Weight Gain .
These include anxiety, agitation, shaking, and tingling or electric shock-like feelings. They also include sweating, nausea, vomiting, strange dreams, dizziness, tiredness, confusion , and headache. If you need to stop taking this drug, your doctor will slowly reduce your dosage over time.
The pivotal original studies supported an FDA-approved antidepressant indication for mirtazapine 15–45 mg /d. While the drug is commonly used off-label at lower doses ( 7.5 to 15 mg at bedtime) primarily for a soporific effect, antidepressant effects at doses of 7.5 mg /d have been reported.
A 2018 study found that people taking antidepressants were 21% more likely to put on weight than those who weren’t prescribed antidepressants. An antidepressant called mirtazapine was associated with the most weight gain .
Mirtazapine ( Remeron ) has a much more sedating effect, generally reducing its potential to aggravate initial anxiety .