Tricyclic antidepressants , especially amitriptyline and dothiepin ,16 are known to pose a high risk of death in overdosage. These drugs should therefore be avoided in older people whose medication is not supervised and who are at risk of taking an overdose.
When it comes to antidepressants for seniors, most experts recommend SSRIs or selective norepinephrine reuptake inhibitors (SNRIs), which help increase the brain chemicals serotonin and norepinephrine. These drugs tend to have fewer serious side effects and drug interactions than older antidepressants on the market.
Selective serotonin reuptake inhibitors ( SSRIs ). These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.
When the researchers checked which depression drugs were tolerated the best, these topped the list: Celexa ( citalopram ) Lexapro ( escitalopram ) Prozac ( fluoxetine ) Trintellix ( vortioxetine ) Zoloft ( sertraline )
Buspirone is an anti-anxiety drug that has been shown to be effective for older adults. Benzodiazepines , another anti-anxiety drug, are effective but should be prescribed carefully to older adults because of risk of memory impairment, unsteadiness, and falls.
Options include citalopram ( Celexa ), fluoxetine ( Prozac ), nortriptyline (Pamelor), paroxetine ( Paxil ), and sertraline ( Zoloft ). Side effects of these medicines can include drowsiness, dry mouth, constipation, and anxiety.
Short-half-life benzodiazepines, such as oxazepam , alprazolam , and triazolam , are usually recommended for older adults, because these agents do not accumulate in the blood, are rapidly cleared from circulation, and offer greater dosage flexibility.
Geriatrics refers to medical care for older adults, an age group that is not easy to define precisely. “Older” is preferred over “elderly,” but both are equally imprecise; > 65 is the age often used, but most people do not need geriatrics expertise in their care until age 70 , 75, or even 80 .
New research links certain medications to dementia risk amitriptyline , paroxetine, and bupropion (most commonly taken for depression) oxybutynin and tolterodine (taken for an overactive bladder) diphenhydramine (a common antihistamine, as found in Benadryl ).
On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine , derived from ketamine —an anesthetic that has made waves for its surprising antidepressant effect.
Several treatments can be used instead of antidepressants for treating depression and other mental health conditions. Talking therapies. Cognitive behavioural therapy. Exercise. Self-help groups. Lithium. Electric shock treatment .
But wait, says Blisstree’s Elizabeth Nolan Brown, who bravely shared her personal story of taking Wellbutrin . Not only did it help her beat smoking and deal with the anxiety after effects of that, she says it also boosted her sex drive and did have appetite-reducing qualities.
Zoloft is the most commonly prescribed antidepressant; nearly 17% of those survey in the 2017 antidepressant use study reported that they had taken this medication. 1 Paxil ( paroxetine ): You might be more likely to have sexual side effects if you choose Paxil over other antidepressants.
Examples of SSRIs are: Prozac ( fluoxetine ) Paxil ( paroxetine ) Zoloft (sertraline) Celexa ( citalopram ) Luvox (fluvoxamine) Lexapro (escitalopram) Trintellix (vortioxetine) Viibryd (vilazodone)
Selective serotonin reuptake inhibitors ( SSRIs ). Generally safe with a low risk of serious side effects, SSRI antidepressants are typically recommended as the first choice of medications to treat panic attacks.