Certain medications. Stimulants for attention-deficit/hyperactivity disorder (ADHD) and illegal stimulants such as amphetamines and cocaine also make you more vulnerable to heatstroke.
Other medications that increase the risk of heat-related illnesses include benzodiazepines, calcium channel blockers, laxatives, neuroleptics, and thyroid agonists. In addition to wearing sunscreen, individuals taking these medications should be urged to avoid staying outdoors on hot days and to drink plenty of fluids.
Commonly used medicines that may significantly increase the risk include diuretics, especially when combined with an angiotensin converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB), anticholinergics and psychotropics.
These common medications can make you more sensitive to the sun:
Some drugs can directly affect the brain’s thermostat and increase body temperature. These include stimulants like Dexedrine and Ritalin. The most dangerous stimulant in this regard is cocaine. Thyroid hormone medications like Synthroid can also elevate body temperature.
Blood pressure medications There’s a risk between heat and high blood pressure medications. Certain prescription treatments for high blood pressure, also known as hypertension, can make you more susceptible to heat intolerance. This is especially true for two types of medications: thiazide diuretics and beta blockers.
Over-the-counter antihistamines whose active ingredient is diphenhydramine (Benadryl) also decreases sweating, resulting in unintended increased body temperatures with harmful heat effects.
Drugs may cause increased body temperature in five ways: altered thermoregulatory mechanisms, drug administration-related fever, fever from the pharmacologic action of the drug, idiosyncratic reactions, and hypersensitivity reactions.
Primary Classes of Medications Responsible for Photosensitizing Reactions
Turns out most high blood pressure medicines make your skin so sun-sensitive that with prolonged use (five years at least) they can trigger lip cancer (which is usually very rare) unless you protect yourself.
You can become photosensitive from: Medications: Some widely used medications, including antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDS), antihistamines and certain heart medicines and statins for lowering cholesterol, can make you far more sensitive to sunlight than you’d usually be.
Beta blockers, like metoprolol, can also make it harder to regulate body temperature. “To radiate heat out of the body and increase the blood flow to the skin, your heart is going to have to work harder and pump faster,” Holm said.
Amlodipine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
A blood thinner works by slowing or impairing the blood’s ability to clot, Dr. Andersen said, and will not make someone feel colder.