AVOID Certain Anticholinergic Drugs
Table. 2015 American Geriatrics Society (AGS) Beers Criteria for Potentially Inappropriate Medication Use in Older Adults
Diphenhydramine and amitriptiline are the most common inappropriately prescribed medications with high risk adverse events while propoxyphene and doxazoxin are the most commonly prescribed medications with low risk adverse events.
Talk with your healthcare provider if a medication you are taking is in the AGS Beers Criteria®. Ask if there might be a safer or more effective alternative. Keep in mind that if a medication you take is on the AGS Beers Criteria®, it still may be a reasonable choice for you.
Anticholinergic drugs should be avoided in patients with dementia, cognitive impairment, or delirium. A study published in JAMA Internal Medicine noted that higher cumulative anticholinergic medication use was associated with an increased risk for dementia.
Gravol can also affect your concentration and movements. Younger children will feel all these effects more than adults. The elderly are more sensitive to these effects, especially if they have delirium or dementia.
Potentially inappropriate medications (PIMs) can be defined as drugs for which use among older adults should be avoided due to the high risk of adverse reactions for this population and/or insufficient evidence of their benefits when safer and equally or more effective therapeutic alternatives are available.
2. Non-benzodiazepine prescription sedatives. These drugs are usually prescribed to treat insomnia or sleep difficulties. This group includes the “z-drugs”: zolpidem, zaleplon, and eszopiclone (brand names Ambien, Sonata, and Lunesta, respectively).
Inappropriate polypharmacy, especially in older people, imposes a substantial burden of adverse drug events, ill health, disability, hospitalization, and even death. The single most important predictor of inappropriate prescribing and risk of adverse drug events in older patients is the number of prescribed drugs.
However, elderly patients may be more sensitive to the effects of this medicine than younger adults, and are more likely to have hyponatremia (low sodium in the blood), which may require caution and an adjustment in the dose for patients receiving paroxetine.
Below are the top 10 medications prescribed to elderly Americans.
However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Drug-drug interactions — Older adults are particularly vulnerable to drug-drug interactions because they often have multiple chronic medical conditions requiring multiple drug therapies. The risk of an adverse event due to drug-drug interactions is substantially increased when multiple drugs are taken [95-99].
Avoid NSAIDs like ibuprofen and naproxen Older adults should be very careful with NSAIDs. Their side effects are especially likely to cause harm as people get older.
5 Over-the-Counter Medicines You Should Never Take Together
Use any form of tramadol with extreme caution in patients 75 years and older. The elderly may be especially prone to side effects with tramadol due to lowered liver or kidney function and reduced metabolism or excretion.