AVOID Certain Anticholinergic Drugs
Diphenhydramine and amitriptiline are the most common inappropriately prescribed medications with high risk adverse events while propoxyphene and doxazoxin are the most commonly prescribed medications with low risk adverse events.
Talk with your healthcare provider if a medication you are taking is in the AGS Beers Criteria®. Ask if there might be a safer or more effective alternative. Keep in mind that if a medication you take is on the AGS Beers Criteria®, it still may be a reasonable choice for you.
A potentially inappropriate medication (PIM) is one prescribed without indication or where the net clinical benefit does not outweigh the risk. PIM use is a common cause of adverse drug reactions in older adults [1,2].
Both Yancy and Clements point out that those medications include: thiazide diuretics (chlorthalidone, hydrochlorothiazide) ACE inhibitors (benazepril, zofenopril, lisinopril, and many others) calcium channel blockers (amlodipine, diltiazem)
The 10 Most Prescribed Medications for the Elderly and What they
Gravol can also affect your concentration and movements. Younger children will feel all these effects more than adults. The elderly are more sensitive to these effects, especially if they have delirium or dementia.
The statistics on medication usage among elderly patients in the US are eye-opening: more than one-third of prescriptions drugs used in the US are taken by elderly patients; the ambulatory elderly fill between 9-13 prescriptions a year (including new prescriptions and refills); the average elderly patient is taking
Anticholinergic drugs should be avoided in patients with dementia, cognitive impairment, or delirium. A study published in JAMA Internal Medicine noted that higher cumulative anticholinergic medication use was associated with an increased risk for dementia.
Medications that increase your risk of falling
However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.
Tertiary amine tricyclics such as amitriptyline and imipramine have been reported to be effective in depressed geriatric patients, but because of their potential for side effects, it is not advisable to use them in the elderly.
The Geriatric Lexi-Drugs database recommends the avoidance of muscle relaxants other than diazepam and tizanidine in patients older than age 65 years because efficacy and safety have not been established in geriatric patients.
Potentially inappropriate medications (PIMs) can be defined as drugs for which use among older adults should be avoided due to the high risk of adverse reactions for this population and/or insufficient evidence of their benefits when safer and equally or more effective therapeutic alternatives are available.
The AGS Beers Criteria® include the same five main categories as in 2015: (1) potentially inappropriate medications in older adults; (2) potentially inappropriate medications to avoid in older adults with certain conditions; (3) medications to be used with considerable caution in older adults; (4) medication