Headache , dizziness , drowsiness , or diarrhea may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. If your doctor has directed you to use this medication, remember that he or she has judged that the benefit to you is greater than the risk of side effects.
After five years’ extensive use of cimetidine, drug interactions have emerged as one of its major adverse effects. Clinically important interactions with warfarin , phenytoin , diazepam, chlormethiazole, propranolol , lidocaine , and a number of other drugs have been reported.
Intracerebroventricular administration of cimetidine or metiamide (2 mumol/rat) increased the blood pressure and heart rate. It is concluded that the hypotension after i.v. cimetidine is mediated by peripheral mechanisms.
Cimetidine is rapidly eliminated, with an elimination half-life of 123 minutes , or about 2 hours . It has been said to have a duration of action of 4 to 8 hours . The medication is mainly eliminated in urine.
Common side effects of cimetidine include: headache . dizziness . sleepiness . enlarged breasts in men. confusion (elderly) impotence. diarrhea . nausea.
If you have mild reflux symptoms that occur less than two times a week, you can start with a low dose of famotidine (Pepcid) or cimetidine (Tagamet).
Over-the-counter cimetidine is usually taken once or twice a day with a glass of water. To prevent symptoms, it is taken within 30 minutes before eating or drinking foods that cause heartburn.
Conclusion: Intake of cimetidine suspension 30 minutes before meals in overweight subjects may lead to reduced hunger, less food intake, and subsequent weight loss . This effect may be due to the suppression of gastric acid secretion. Cimetidine suspension may be a valuable adjunct in treating obesity.
Cimetidine 200mg tablets are out of stock until the end of January 2020.
Omeprazole is more effective than cimetidine for the relief of all grades of gastro-oesophageal reflux disease-associated heartburn, irrespective of the presence or absence of endoscopic oesophagitis.
Abstract. Ranitidine , a new H2-receptor blocking antihistamine, is pharmacokinetically similar to cimetidine , but its potency is about eightfold greater.
Zantac, generics ordered off the market after FDA finds they’re a ticking time bomb. Nearly four decades after it was approved, the FDA has ordered that heartburn drug Zantac and its generics be removed from the market , saying they have been exposing consumers to the risk of cancer.
Avoid cimetidine ( Tagamet ) for heartburn because it can lead to a rise in creatinine levels in the blood, making it seem as if your kidney function has worsened.
Too many androgens and too much DHT may be the reason behind hair loss , and cimetidine potentially affects both of those hormones.
They lower the amount of acid in your stomach, but studies have shown that taking them for a long time can raise your chances of serious kidney problems and possibly lead to kidney failure. Other heartburn medicines called H2 blockers (Pepcid, Tagamet , Zantac ) are less likely to cause these issues.