Atorvastatin or fluvastatin are usually recommended because there is no need to adjust the dose according to the glomerular filtration rate . In patients without diagnosed atherosclerotic cardiovascular disease, it is indicated a moderate dose of statin, such as atorvastatin 20 mg daily .Oct 30, 2019
In the analysis of 135 previous studies, which included nearly 250,000 people combined, researchers found that the drugs simvastatin ( Zocor ) and pravastatin ( Pravachol ) had the fewest side effects in this class of medications . They also found that lower doses produced fewer side effects in general.
Adults age 75 and older may not need statins . Many older adults have high cholesterol. Their doctors usually prescribe statins to prevent heart disease. But for older people, there is no clear evidence that high cholesterol leads to heart disease or death.
Most societies, including the ACC and AHA, recommend shared decision making in this subgroup of patients. Now, a new study published this past week in the European Heart Journal suggests that discontinuing statins in patients older than 75 years of age may actually increase the risk of hospital admissions by 33%.
Guidelines in the United States recommend statin therapy for primary prevention in men and women regardless of age . The guidelines from the European Society of Cardiology, however, do not provide recommendations for statin use in older people , Fonarow said.
Telomerase activity is associated with longer telomeres. Statins do have side effects, all medication does to some extent. And some of those side effects reported could also be deemed to be signs of premature aging. Memory loss and weakness or fatigue are both listed under ‘uncommon side effects’ on the NHS website.
Very rarely, statins can cause life-threatening muscle damage called rhabdomyolysis (rab-doe-my-OL-ih-sis). Rhabdomyolysis can cause severe muscle pain, liver damage, kidney failure and death. The risk of very serious side effects is extremely low, and calculated in a few cases per million people taking statins .
Which Statin is Better : Lipitor or Crestor ? Lipitor and Crestor are both effective statins that lower levels of “bad” cholesterol and increase levels of “ good ” cholesterol. While Crestor is the more potent statin, both medications are effective and have slightly different side effects and drug interactions.
Statins are typically very successful at lowering cholesterol, but they only work as long as you ‘ re taking them. Therefore, most people who begin taking a statin medication will likely take it for the rest of their lives.
If your risk is low, taking a statin or any cholesterol-lowering drug could do more harm than good . Statins have side effects — they can cause liver and muscle damage — and they require close monitoring.
Statin drugs have been shown to reduce the risk of cardiovascular disease (CVD) in young and middle-aged adults. With older adults (those 75 and over), the benefits are less clear. But a recent study published in the European Heart Journal suggests that there is in fact a benefit to statin use in this older population.
In general, healthy cholesterol levels for seniors are total cholesterol of below 200 mg/dl, including an LDL cholesterol level less than 100 mg/dl, and an HDL cholesterol level greater than 40 mg/dl for men or 50 mg/dl for women.
Evidence for Statins Increasing Risk of Dementia Simvastatin, atorvastatin, and pravastatin were the medications taken by the patients who were described. About half of these patients noticed cognitive problems within two months of starting treatment.
Statins help lower low-density lipoprotein (LDL) cholesterol, also known as “bad” cholesterol, in the blood. They draw cholesterol out of plaque and stabilize plaque , Blaha says.
A few changes in your diet can reduce cholesterol and improve your heart health: Reduce saturated fats. Saturated fats, found primarily in red meat and full-fat dairy products, raise your total cholesterol . Eliminate trans fats. Eat foods rich in omega-3 fatty acids. Increase soluble fiber. Add whey protein.
Ezetimibe. Ezetimibe is a tablet that lowers cholesterol. It may be prescribed if statins cannot be taken, or alongside a statin for extra cholesterol-lowering. It’s a ‘cholesterol absorption inhibitor’ that limits the absorption of cholesterol in the small intestine.