Choice of antidepressant The selective serotonin reuptake inhibitors (SSRIs) and the newer antidepressants buproprion, mirtazapine , moclobemide, and venlafaxine (a selective norepinephrine reuptake inhibitor or SNRI) are all relatively safe in the elderly.
Selective serotonin reuptake inhibitors ( SSRIs ). These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.
When the researchers checked which depression drugs were tolerated the best, these topped the list: Celexa ( citalopram ) Lexapro ( escitalopram ) Prozac ( fluoxetine ) Trintellix ( vortioxetine ) Zoloft ( sertraline )
Sertraline is generally well tolerated in elderly patients with major depressive disorder and lacks the marked anticholinergic effects that characterise the adverse event profiles of tricyclic antidepressants (TCAs).
Buspirone is an anti-anxiety drug that has been shown to be effective for older adults. Benzodiazepines , another anti-anxiety drug, are effective but should be prescribed carefully to older adults because of risk of memory impairment, unsteadiness, and falls.
Many drugs that act on the brain can cause delirium, including narcotic painkillers, sedatives (particularly benzodiazepines), stimulants, sleeping pills, antidepressants , Parkinson’s disease medications, and antipsychotics.
Zoloft is the most commonly prescribed antidepressant; nearly 17% of those survey in the 2017 antidepressant use study reported that they had taken this medication. 1 Paxil ( paroxetine ): You might be more likely to have sexual side effects if you choose Paxil over other antidepressants.
On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine , derived from ketamine —an anesthetic that has made waves for its surprising antidepressant effect.
Several treatments can be used instead of antidepressants for treating depression and other mental health conditions. Talking therapies. Cognitive behavioural therapy. Exercise. Self-help groups. Lithium. Electric shock treatment .
Examples of SSRIs are: Prozac ( fluoxetine ) Paxil ( paroxetine ) Zoloft (sertraline) Celexa ( citalopram ) Luvox (fluvoxamine) Lexapro (escitalopram) Trintellix (vortioxetine) Viibryd (vilazodone)
Another anti-anxiety drug is busprirone ( Buspar ). It has fewer side effects than the benzodiazepines and is not associated with dependence.
Selective serotonin reuptake inhibitors ( SSRIs ). Generally safe with a low risk of serious side effects, SSRI antidepressants are typically recommended as the first choice of medications to treat panic attacks.
With the exception of paroxetine, the long-term use of most antidepressants does not increase dementia risk, suggests a study published in the Journal of the American Geriatrics Society.
Short-half-life benzodiazepines, such as oxazepam , alprazolam , and triazolam , are usually recommended for older adults, because these agents do not accumulate in the blood, are rapidly cleared from circulation, and offer greater dosage flexibility.
Options include citalopram ( Celexa ), fluoxetine ( Prozac ), nortriptyline (Pamelor), paroxetine ( Paxil ), and sertraline ( Zoloft ). Side effects of these medicines can include drowsiness, dry mouth, constipation, and anxiety.